Product Description

Shilstine 50mg Injection contains the active constituent leucovorin calcium. It is used to reduce the side effects of a group of medicines called folic acid antagonists such as methotrexate (anticancer medicine), trimetrexate (antibiotic and anticancer medicine), trimethoprim (antibiotic) and pyrimethamine (antimalarial medication). It is used to treat megaloblastic anemias caused by folic acid deficiency. 

Shilstine 50mg Injection is also used to increase the effectiveness of fluorouracil (anticancer medicine). It is not recommended for patients with anemia caused by too little vitamin B12. Talk to your doctor if you are pregnant, breastfeeding, have had radiotherapy or stomach problems before taking this medicine. Large quantities of Leucovorin may diminish the chemotherapeutic effect of folic acid antagonists.Make sure you inform your physician of all the medicines, including supplements and herbal medicines, you are taking before you start treatment with Shilstine 50mg Injection. Nausea, diarrhea, and vomiting are very common side effects of this medicine.

How to use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Uses

Treatment of Methotrexate Toxicity

Side Effects

Serious:                   

• Fainting
• Seizures
• Gastrointestinal  toxicity
• Urticaria and Anaphylactic reactions

Common:

• Nausea, vomiting,
• Diarrhea
• Constipation
• Low blood count
• Infection
• Lethargy, fatigue
• Hair loss
• Dermatitis
• Anorexia

Storage

Store in a refrigerator (2 - 8)℃