Product Description

Spnib 50mg Tablet is prescribed for adults and children above one year of age with Chronic Myeloid Leukemia. This medicine is used to treat newly diagnosed Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) in the chronic phase and Ph+ acute lymphoblastic leukemia in patients resistant to other therapies.  

Chronic Myeloid Leukemia refers to a type of blood cancer that makes the body produce too many white blood cells that happen due to alteration in the Philadelphia chromosome. The abnormality in this chromosome causes fusion of BCR and ABL gene that codes for proteins with tyrosine kinase activity, which, in turn, influences cell multiplication, division and survival.Acute Lymphoblastic Leukemia is the most common form of blood cancer that affects children. In this case, the lymphocytes of white blood cells multiply too quickly and live too long.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

How to use

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Spnib 50mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

Uses

Treatment of Blood cancer

Side Effects

Serious:

• Unusual bleeding or bruising
• Rapid heart rate
• Changes in consciousness or speech
• Breathlessness and swelling all over the body
• Fever or signs of infection
• Fluid retention
• Heart problems
• Myelosuppression
• Severe allergic reaction

Common:

• Diarrhea
• Headache
• Cough
• Rash
• Nausea, tiredness, vomiting
• Muscle pain, weakness
• Low appetite
• High or low BP

Storage

Store below 30℃