Product Description

Intensic 100mg Injection consists of the active ingredient Irinotecan hydrochloride trihydrate, indicated for advanced colon cancer and rectum cancer in adults. It is prescribed alone or as a combination with other chemotherapeutic agents.

Cancer in the colon and rectum is prevalent in age groups above 50 years and is further triggered by genetic and environmental factors. The symptoms of this cancer depend on the site at which the tumor is formed.Myelosuppression (bone marrow suppression leading to low levels of RBC, WBC and platelets in blood) and diarrhea are the most commonly occuring adverse effects of this drug. An early form of diarrhea occurs within 24 hours of administering this drug. It is regarded as a cholinergic event. Late form of diarrhea usually occurs 2-10 days after the treatment. This is more severe, leading to electrolyte imbalance and dehydration.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

How to use

Your doctor or nurse will give you this medicine. Kindly do not self administer.

Uses

Treatment of Colorectal cancer

Side Effects

Serious:

• Early and late diarrhea
• Allergic reactions
• Kidney impairment
• Lung problems
• Low levels of RBC, WBC and platelets in the blood

Common:

• Nausea, vomiting, abdominal pain
• Constipation
• Anaemia
• Pain
• Fever
• Infection
• Abnormal bilirubin levels
• Hair loss
• Weight loss

Storage

Store below 30℃